Inversion of the Chromosomal Region between Two Mating Type Loci Switches the Mating Type in Hansenula polymorpha

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Inversion of the Chromosomal Region between Two Mating Type Loci Switches the Mating Type in Hansenula polymorpha

Yeast mating type is determined by the genotype at the mating type locus (MAT). In homothallic (self-fertile) Saccharomycotina such as Saccharomyces cerevisiae and Kluveromyces lactis, high-efficiency switching between a and α mating types enables mating. Two silent mating type cassettes, in addition to an active MAT locus, are essential components of the mating type switching mechanism. In thi...

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Fungal mating-type loci

Fungi form one of the most ubiquitous and successful kingdoms of life on Earth. There are more than 100,000 known species of fungi, divided into four phyla — ascomycetes, basidiomycetes, zygomycetes and chytrids — and these have populated a vast array of biological niches, including those that are pathogens of animals (including humans and insects), plants and even other microorganisms. The mor...

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Silent Mating-Type Loci in Fission Yeast

In Schizosaccharomyces Pombe the mating-type information is stored at two transcriptionally silent loci (mat2 and mat3). The region between these sites ( K region) is inert for meiotic crossing over. The mating-type genes (M or P) are expressed only when present at a third, active locus (matl). We have earlier shown that the positional regulation of P genes is based on repression at the silent ...

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Gene organization of the mating type regions in the ectomycorrhizal fungus Laccaria bicolor reveals distinct evolution between the two mating type loci.

In natural conditions, basidiomycete ectomycorrhizal fungi such as Laccaria bicolor are typically in the dikaryotic state when forming symbioses with trees, meaning that two genetically different individuals have to fuse or 'mate'. Nevertheless, nothing is known about the molecular mechanisms of mating in these ecologically important fungi. Here, advantage was taken of the first sequenced genom...

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ژورنال

عنوان ژورنال: PLoS Genetics

سال: 2014

ISSN: 1553-7404

DOI: 10.1371/journal.pgen.1004796